Neutral sphingomyelinase-3 mediates TNF-stimulated oxidant activity in skeletal muscle
نویسندگان
چکیده
منابع مشابه
Neutral sphingomyelinase-3 mediates TNF-stimulated oxidant activity in skeletal muscle
AIMS Sphingolipid and oxidant signaling affect glucose uptake, atrophy, and force production of skeletal muscle similarly and both are stimulated by tumor necrosis factor (TNF), suggesting a connection between systems. Sphingolipid signaling is initiated by neutral sphingomyelinase (nSMase), a family of agonist-activated effector enzymes. Northern blot analyses suggest that nSMase3 may be a str...
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ژورنال
عنوان ژورنال: Redox Biology
سال: 2014
ISSN: 2213-2317
DOI: 10.1016/j.redox.2014.07.006